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Version: 17.06d (Release date: 2017-06-26)
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Dimethylmyleran (Code C1073)

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Terms & Properties

Preferred Name: Dimethylmyleran

Definition: An aliphatic analogue of busulfan with potential antineoplastic activity. As an alkylating agent, dimethylbusulfan induces neutropenia and has been shown to exhibit antitumor effects in some animal models. Alkylating agents exert cytotoxic and chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04)

Label: Dimethylmyleran

NCI Thesaurus Code: C1073 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0058272  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
2,5-Dimethanesulfonoxyhexane
Dimethyl-Myleran
Dimethylbusulfan
Dimethylmyleran
DMB
DMM

External Source Codes: 
CAS Registry Number 55-93-6 (see NLM ChemIDplus info)
NSC Code 180541 (see NCI DTP info)
NSC Code 180542 (see NCI DTP info)
NSC Code 180543 (see NCI DTP info)
NSC Code 23890 (see NCI DTP info)
PDQ Closed Trial Search ID 39221
PDQ Open Trial Search ID 39221 (check for NCI PDQ open clinical trial info)
UMLS CUI C0058272

Other Properties:
     Name Value (qualifiers indented underneath)
code C1073
Legacy_Concept_Name Dimethylbusulfan
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1073

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