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Version: 17.06d (Release date: 2017-06-26)
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pBCAR3 Phosphopeptide-tetanus Peptide Vaccine (Code C107166)

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Terms & Properties

Preferred Name: pBCAR3 Phosphopeptide-tetanus Peptide Vaccine

Definition: A vaccine composed of a phosphorylated peptide from the tumor associated antigen breast cancer anti-estrogen resistance-3 (BCAR3) and a tetanus-derived peptide, with potential immunomodulating and antineoplastic activities. Upon administration of pBCAR3 phosphopeptide-tetanus peptide vaccine, the pBCAR3 phosphopeptide may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against phosphopeptide-containing tumor cells. The tetanus peptide serves as an immunoadjuvant and induces a helper T-cell response, which may help stimulate an immune response against the pBCAR3-expressing melanoma tumor cells. BCAR3 is upregulated in a variety of cancer cells.

Label: pBCAR3 Phosphopeptide-tetanus Peptide Vaccine

NCI Thesaurus Code: C107166 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL449426  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
pBCAR3-phosphopeptide Plus Tet Vaccine
pBCAR3 Phosphopeptide-tetanus Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 750408
PDQ Open Trial Search ID 750408 (check for NCI PDQ open clinical trial info)
NCI META CUI CL449426

Other Properties:
     Name Value (qualifiers indented underneath)
code C107166
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C107166

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