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Version: 17.06d (Release date: 2017-06-26)
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Heparan Sulfate Glycosaminoglycan Mimetic Nanopolymer Mouthwash (Code C107161)

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Terms & Properties

Preferred Name: Heparan Sulfate Glycosaminoglycan Mimetic Nanopolymer Mouthwash

Definition: A nanopolymer-based mouthwash formulation containing a mimetic of the glycosaminoglycan (GAG) heparan sulfate, with potential anti-mucositic and protective activities. Upon rinsing with the mouthwash, GAGs bind to heparan sulfate binding sites on macromolecules within the extracellular matrix (EMC), which prevents the destruction of the ECM and protects both growth factors and cytokines from being degraded. By replacing the GAGs damaged by chemotherapy and/or radiation, this mouthwash may protect healthy tissue against the cytotoxic effects of chemotherapy and radiation and may prevent against radio-chemotherapy-induced mucositis.

Label: Heparan Sulfate Glycosaminoglycan Mimetic Nanopolymer Mouthwash

NCI Thesaurus Code: C107161 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL449422  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Heparan Sulfate Glycosaminoglycan Mimetic Nanopolymer Mouthwash
MUCIPLIQ Mouthwash

External Source Codes: 
PDQ Closed Trial Search ID 750277
PDQ Open Trial Search ID 750277 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C107161
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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