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Version: 17.06d (Release date: 2017-06-26)
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Zirconium Zr 89-labeled Monoclonal Antibody MMOT0530A (Code C106367)

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Terms & Properties

Preferred Name: Zirconium Zr 89-labeled Monoclonal Antibody MMOT0530A

Definition: A radioimmunoconjugate composed of a monoclonal antibody that targets an antigen overexpressed in pancreatic and ovarian cancer and labeled with the radioisotope zirconium Zr 89, with potential use for assessing tumor antigen expression using positron emission tomography (PET). Upon administration of zirconium Zr 89-labeled monoclonal antibody MMOT0530A, this agent targets an antigen expressed on certain tumor cells and is internalized. Following tumor cell uptake, the radioisotope moiety can be visualized using PET imaging. This may result in both the quantification of tumor antigen expression and an assessment of the response to treatment with therapeutics targeting the antigen.

Label: Zirconium Zr 89-labeled Monoclonal Antibody MMOT0530A

NCI Thesaurus Code: C106367 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL447734  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
89Zr-MMOT
89Zr-MMOT0530A
Zirconium Zr 89-labeled Monoclonal Antibody MMOT0530A

External Source Codes: 
PDQ Closed Trial Search ID 749474
PDQ Open Trial Search ID 749474 (check for NCI PDQ open clinical trial info)
NCI META CUI CL447734

Other Properties:
     Name Value (qualifiers indented underneath)
code C106367
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C106367

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