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Version: 17.12d (Release date: 2017-12-26)
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Olive Oil Extract/Curcumin-based Capsule (Code C106234)

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Terms & Properties

Preferred Name: Olive Oil Extract/Curcumin-based Capsule

Definition: A capsule containing an extract of olive oil, rich in polyphenols, and curcumin, the polyphenol derived from the plant Curcuma longa, also known as turmeric, with potential anti-neoplastic, -angiogenic, -inflammatory, -oxidant and chemopreventive activities. The olive oil extract/curcumin-based capsule is rich in phytonutrients, especially polyphenols. Upon oral administration, the polyphenols, and other active ingredients in this supplement may exert anti-inflammatory activity by decreasing the production of inflammation mediators, such as TNF-alpha, interleukin (IL) 1-beta, IL-6, IL-10, interferon gamma, thromboxane B2, and leukotriene B4. They also inhibit a variety of pro-inflammatory enzymes, such as cyclooxygenase 1 (COX-1) and COX-2, block the formation of reactive-oxygen species and neutralize free radicals. In addition, curcumin and some other polyphenols disrupt cell signal transduction pathways involved in carcinogenesis. Specifically, curcumin inhibits cell invasion by inhibiting matrix metalloproteinase-9 (MMP-9) expression by suppressing NF-kB and AP-1 activation.

Label: Olive Oil Extract/Curcumin-based Capsule

NCI Thesaurus Code: C106234 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL447409  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Olive Oil Extract/Curcumin-based Capsule
PhytoMed Medical Food Suppement

External Source Codes: 
PDQ Closed Trial Search ID 748887
PDQ Open Trial Search ID 748887 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C106234
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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