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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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UV1 Telomerase Peptide Vaccine (Code C104747)

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Terms & Properties

Preferred Name: UV1 Telomerase Peptide Vaccine

Definition: A synthetic, peptide cancer vaccine directed against the human telomerase reverse transcriptase catalytic subunit (hTERT) with potential immunomodulating activity. Vaccination with the UV1 telomerase peptide may stimulate cytotoxic T-cells to recognize and kill telomerase-expressing cells. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation.

Label: UV1 Telomerase Peptide Vaccine

NCI Thesaurus Code: C104747 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL445818  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
UV1/hTERT Peptide Vaccine
UV1 Telomerase Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 746230
PDQ Open Trial Search ID 746230 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C104747
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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