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Version: 17.06d (Release date: 2017-06-26)
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WT1 235-243 Peptide Vaccine (Code C104734)

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Terms & Properties

Preferred Name: WT1 235-243 Peptide Vaccine

Definition: A synthetic peptide vaccine consisting of a HLA-A24-restricted human Wilms' Tumor protein-1 (WT1) peptide comprised of amino acids 235 through 243, a MHC class I-restricted peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 235-243 peptide may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers.

Display Name: WT1 235-243 Peptide Vaccine

Label: WT1 235-243 Peptide Vaccine

NCI Thesaurus Code: C104734 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL445808  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
WT1 235-243 Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 746008
PDQ Open Trial Search ID 746008 (check for NCI PDQ open clinical trial info)
NCI META CUI CL445808

Other Properties:
     Name Value (qualifiers indented underneath)
code C104734
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C104734

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