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Version: 17.06d (Release date: 2017-06-26)
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Pegfilgrastim Biosimilar LA-EP2006 (Code C104005)

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Terms & Properties

Preferred Name: Pegfilgrastim Biosimilar LA-EP2006

Definition: A biosimilar of pegfilgrastim, a long-acting pegylated form of recombinant human granulocyte colony-stimulating factor (G-CSF) filgrastim, with hematopoietic activity. In a similar manner to G-CSF, pegfilgrastim biosimilar LA-EP2006 binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. Therefore, this agent may prevent the incidence and shorten the duration of chemotherapy-induced neutropenia. Conjugation of the cytokine with a branched polyethylene glycol molecule significantly increases this agent's therapeutic half-life compared to filgrastim.

Label: Pegfilgrastim Biosimilar LA-EP2006

NCI Thesaurus Code: C104005 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL433964  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
LA-EP2006
Pegfilgrastim Biosimilar LA-EP2006

External Source Codes: 
PDQ Closed Trial Search ID 743382
PDQ Open Trial Search ID 743382 (check for NCI PDQ open clinical trial info)
NCI META CUI CL433964

Other Properties:
     Name Value (qualifiers indented underneath)
code C104005
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C104005

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