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Version: 17.06d (Release date: 2017-06-26)
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Long-acting Granulocyte Colony-stimulating Factor Analog SPI-2012 (Code C103856)

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Terms & Properties

Preferred Name: Long-acting Granulocyte Colony-stimulating Factor Analog SPI-2012

Definition: A long-acting, recombinant analog of the endogenous human granulocyte colony-stimulating factor (G-CSF) with hematopoietic activity. Similar to G-CSF, long-acting G-CSF analog SPI-2012 binds to and activates specific cell surface receptors and stimulates neutrophil progenitor proliferation and differentiation, as well as selected neutrophil functions. Therefore, this agent may decrease the duration and incidence of chemotherapy-induced neutropenia. The long-acting G-CSF analog SPI-2012 extends the half-life of G-CSF, allowing for administration once every 3 weeks.

Display Name: Long-acting Granulocyte Colony-stimulating Factor Analog SPI-2012

Label: Long-acting Granulocyte Colony-stimulating Factor Analog SPI-2012

NCI Thesaurus Code: C103856 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C3641655  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
HM10460A
LAPS-GCSF
Long-acting Granulocyte Colony-stimulating Factor Analog SPI-2012
SPI-2012

External Source Codes: 
PDQ Closed Trial Search ID 743098
PDQ Open Trial Search ID 743098 (check for NCI PDQ open clinical trial info)
UMLS CUI C3641655

Other Properties:
     Name Value (qualifiers indented underneath)
code C103856
Contributing_Source CTRP
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C103856

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