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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Carbogen (Code C1038)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Carbogen

Definition: An inhalant consisting of hyperoxic gas (95%-98% oxygen and 2%-5% carbon dioxide) with radiosensitizing properties. Inhaled carbogen reduces diffusion-limited tumor hypoxia, increasing tumor radiosensitivity due to the increased availability of molecular oxygen for cytotoxic radiation-induced oxygen free radical production. (NCI04)

NCI-GLOSS Definition: An inhalant of oxygen and carbon dioxide that increases the sensitivity of tumor cells to the effects of radiation therapy.

Label: Carbogen

NCI Thesaurus Code: C1038 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0054692  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Carbogen
carbogen

External Source Codes: 
CAS Registry Number 8063-77-2 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 42043
PDQ Open Trial Search ID 42043 (check for NCI PDQ open clinical trial info)
UMLS CUI C0054692

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For inhalation therapy to produce vasodilation.
code C1038
Legacy_Concept_Name Carbogen
Semantic_Type Inorganic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1038

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