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National Cancer Institute
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Version: 16.10e (Release date: 2016-10-31)
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Iodine I 131 Rituximab (Code C102981)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Iodine I 131 Rituximab

Definition: A radioimmunoconjugate comprised of rituximab, a recombinant chimeric monoclonal antibody directed against the CD20 antigen, and labeled with iodine I 131 with potential antineoplastic activity. The antibody moiety of iodine I 131 rituximab binds to the CD20 antigen thereby delivering cytotoxic iodine I 131 specifically to cancer cells expressing CD20. The CD20 antigen, a hydrophobic transmembrane protein, is expressed on normal pre-B and mature B lymphocytes.

Label: Iodine I 131 Rituximab

NCI Thesaurus Code: C102981 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1676077  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(131)I-Rituximab
131I-Rituxan
Iodine I 131 Rituximab

External Source Codes: 
PDQ Closed Trial Search ID 739942
PDQ Open Trial Search ID 739942 (check for NCI PDQ open clinical trial info)
UMLS CUI C1676077

Other Properties:
Name Value (qualifiers indented underneath)
code C102981
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C102981

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