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Version: 17.06d (Release date: 2017-06-26)
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hTERT/Survivin/CMV Multipeptide Vaccine (Code C102879)

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Terms & Properties

Preferred Name: hTERT/Survivin/CMV Multipeptide Vaccine

Definition: A vaccine containing multiple peptides derived from the human telomerase reverse transcriptase (hTERT), survivin and cytomegalovirus (CMV), with potential immunostimulating and antineoplastic activities. Upon administration, hTERT/survivin/CMV multipeptide vaccine may elicit a cytotoxic T cell (CTL) response against tumor cells espressing hTERT, survivin and CMV. hTERT, the catalytic subunit of telomerase, and the inhibitor of apoptosis (IAP) family member survivin, both often upregulated in tumor cells, play key roles in tumor cell growth and survival. Further, CMV expression is correlated with certain types of cancer.

Display Name: hTERT/Survivin/CMV Multipeptide Vaccine

Label: hTERT/Survivin/CMV Multipeptide Vaccine

NCI Thesaurus Code: C102879 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL437182  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
hTERT/Survivin/CMV Multipeptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 738632
PDQ Open Trial Search ID 738632 (check for NCI PDQ open clinical trial info)
NCI META CUI CL437182

Other Properties:
     Name Value (qualifiers indented underneath)
code C102879
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C102879

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