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Version: 17.06d (Release date: 2017-06-26)
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Boanmycin Hydrochloride (Code C102878)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Boanmycin Hydrochloride

Definition: The hydrochloride salt form of boanmycin (aka bleomycin A6), a component of the antibiotic bleomycin produced by Streptomyces species, with potential antineoplastic activity. Upon administration, boanmycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals. This causes single- and double-stranded DNA breaks which eventually leads to cell death. Compared to bleomycin, boanmycin appears to have a more favorable toxicity profile.

Label: Boanmycin Hydrochloride

NCI Thesaurus Code: C102878 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL437181  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BAM HCl
Bleomycin A6 Hydrochloride
Boanmycin Hydrochloride

External Source Codes: 
PDQ Closed Trial Search ID 738501
PDQ Open Trial Search ID 738501 (check for NCI PDQ open clinical trial info)
NCI META CUI CL437181

Other Properties:
     Name Value (qualifiers indented underneath)
code C102878
Semantic_Type Antibiotic

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C102878

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