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Version: 17.06d (Release date: 2017-06-26)
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Vaccinium myrtillus/Macleaya cordata/Echinacea angustifolia Extract Granules (Code C102748)

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Terms & Properties

Preferred Name: Vaccinium myrtillus/Macleaya cordata/Echinacea angustifolia Extract Granules

Definition: A proprietary suspension formulation prepared from granules of standardized extracts from the fruits of Vaccinium myrtillus, the aerial parts of Macleaya cordata and the roots of Echinacea angustifolia, with potential anti-mucositis, anti-inflammatory, and analgesic activities. The main active ingredients of this formulation include anthocyanosides and procyanidins, benzophenanthridinic alkaloids, and alkylamides from V. myrtillus, M. cordata and E. angustifolia extracts, respectively. Upon administration in the mucosal cavity, the anthocyanosides scavenge free radicals, form a protective barrier on the mucosa, and protect the integrity of the capillary vessels; the benzophenanthridine alkaloids prevent the production of pro-inflammatory cytokines by inhibiting NF-kB and may halt the growth of microorganisms; the alkylamides inhibit cyclooxygenase and 5-lipoxygenase thereby blocking productions of prostaglandin and leukotriene. Furthermore, alkylamides modulate the expression of tumor necrosis factor alpha and other cytokines involved in inflammation processes through cannabinoid type 2 receptors and as cannabinomimetics they may also exert analgesic activity.

Display Name: Vaccinium myrtillus/Macleaya cordata/Echinacea angustifolia Extract Granules

Label: Vaccinium myrtillus/Macleaya cordata/Echinacea angustifolia Extract Granules

NCI Thesaurus Code: C102748 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL437005  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Samital Granules
V. myrtillus/M. cordata/E. angustfolia Extract Granules
Vaccinium myrtillus/Macleaya cordata/Echinacea angustifolia Extract Granules

External Source Codes: 
PDQ Closed Trial Search ID 735790
PDQ Open Trial Search ID 735790 (check for NCI PDQ open clinical trial info)
NCI META CUI CL437005

Other Properties:
     Name Value (qualifiers indented underneath)
code C102748
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C102748

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