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Version: 17.06d (Release date: 2017-06-26)
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Saccharomyces boulardii Probiotic Supplement (Code C102567)

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Terms & Properties

Preferred Name: Saccharomyces boulardii Probiotic Supplement

Definition: A probiotic containing the non-pathogenic yeast Saccharomyces boulardii with antidiarrheal and potential anti-inflammatory, antimicrobial and immunomodulating activities. As a dietary supplement, S. boulardii may improve digestion and help maintain adequate colonization of the gastrointestinal (GI) tract by modulating the composition of the normal intestinal microflora. During colonization of the GI tract, S. boulardii forms a protective barrier that helps maintain the integrity of the epithelial barrier. This prevents attachment of pathogens to the intestinal mucosa. In addition, this probiotic secretes a protease that binds to and degrades toxins A and B produced by Clostridium difficile, thereby preventing their harmful effects. Dietary supplementation with this bacterium may reduce the secretion of proinflammatory cytokines and may potentiate natural and acquired immunity.

Label: Saccharomyces boulardii Probiotic Supplement

NCI Thesaurus Code: C102567 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL436874  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
S. boulardii Probiotic
Saccharomyces boulardii Probiotic Supplement

External Source Codes: 
PDQ Closed Trial Search ID 735160
PDQ Open Trial Search ID 735160 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C102567
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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