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National Cancer Institute
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Version: 17.08d (Release date: 2017-08-28)
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Adenovirus-PSA Prostate Cancer Vaccine (Code C102541)

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Terms & Properties

Preferred Name: Adenovirus-PSA Prostate Cancer Vaccine

Definition: A cancer vaccine composed of a genetically engineered, replication-deficient type 5 adenovirus carrying the human prostate-specific antigen (PSA), with potential immunostimulating and antineoplastic activities. Upon subcutaneous vaccination with the adenovirus-PSA prostate cancer vaccine, the adenovirus infects cells and expresses PSA. In turn, PSA may activate the immune system and may induce a cytotoxic T-lymphocyte response against PSA-expressing tumor cells. PSA, a tumor associated antigen, is expressed by prostate epithelial cells and is overexpressed in prostate cancer.

Display Name: Adenovirus-PSA Prostate Cancer Vaccine

Label: Adenovirus-PSA Prostate Cancer Vaccine

NCI Thesaurus Code: C102541 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL436813  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Ad/PSA Vaccine
Adenovirus-PSA Prostate Cancer Vaccine
Adenovirus/PSA Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 734505
PDQ Open Trial Search ID 734505 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C102541
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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