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Version: 17.06d (Release date: 2017-06-26)
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Epidermal Growth Factor Ointment (Code C101890)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Epidermal Growth Factor Ointment

Definition: A topical ointment containing a recombinant form of human epidermal growth factor (EGF) with potential protective activity against EGF receptor (EGFR/HER1) inhibitor-induced cutaneous toxicities. Upon topical application of the EGF ointment, EGF locally activates EGFR, thereby abrogating EGFR inhibition in the skin caused by systemic EGFR inhibiting agents. This may help inhibit the skin rash induced by EGFR antagonists. EGFR, a tyrosine kinase, plays a key role in maintaining epidermal integrity.

Label: Epidermal Growth Factor Ointment

NCI Thesaurus Code: C101890 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL436273  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
EGF Ointment
Epidermal Growth Factor Ointment
Sesal Yeongo

External Source Codes: 
PDQ Closed Trial Search ID 733828
PDQ Open Trial Search ID 733828 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C101890
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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