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Version: 17.06d (Release date: 2017-06-26)
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EGFR Inhibitor HM61713 (Code C101791)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: EGFR Inhibitor HM61713

Definition: An orally available small molecule, mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. EGFR inhibitor HM61713 binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild type form.

Display Name: EGFR Inhibitor HM61713

Label: EGFR Inhibitor HM61713

NCI Thesaurus Code: C101791 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL435909  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
EGFR Inhibitor HM61713
HM61713

External Source Codes: 
PDQ Closed Trial Search ID 733621
PDQ Open Trial Search ID 733621 (check for NCI PDQ open clinical trial info)
NCI META CUI CL435909

Other Properties:
     Name Value (qualifiers indented underneath)
code C101791
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C101791

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