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Version: 17.06d (Release date: 2017-06-26)
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Iobenguane I-124 (Code C101776)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Iobenguane I-124

Definition: A radioconjugate composed of the positron-emitting radioisotope iodine I 124 labeled to iobenguane, the synthetic aralkylguanidine analogue of the neurotransmitter norepinephrine (NE), with potential diagnostic imaging applications upon positron emitting tomography (PET) or computed tomography (CT). Upon administration, iobenguane I-124 is taken up and accumulates in the granules of adrenal medullary chromaffin cells and in the pre-synaptic granules of adrenergic neurons in a manner almost identical with that of NE. In turn, tumor cells can be imaged upon PET or CT.

Display Name: Iobenguane I-124

Label: Iobenguane I-124

NCI Thesaurus Code: C101776 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL435900  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
124I-metaiodobenzylguanidine
124I-MIBG
Iobenguane I-124
IOBENGUANE I-124
Iodine I 124 Iobenguane
Iodine I 124 Metaiodobenzylguanidine

External Source Codes: 
FDA UNII Code K2349O62GE
PDQ Closed Trial Search ID 732715
PDQ Open Trial Search ID 732715 (check for NCI PDQ open clinical trial info)
NCI META CUI CL435900

Other Properties:
     Name Value (qualifiers indented underneath)
code C101776
Contributing_Source CTRP
Contributing_Source FDA
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C101776

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