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Version: 16.11d (Release date: 2016-11-28)
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Beta-Carotene (Code C1016)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Beta-Carotene

Definition: A naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. This agent also induces cell differentiation and apoptosis of some tumor cell types, particularly in early stages of tumorigenesis, and enhances immune system activity by stimulating the release of natural killer cells, lymphocytes, and monocytes. (NCI04)

NCI-GLOSS Definition: A substance found in yellow and orange fruits and vegetables and in dark green, leafy vegetables. The body can make vitamin A from beta carotene. Beta carotene is being studied in the prevention of some types of cancer. It is a type of antioxidant.

CRCH Definition: Carotenoid consisting of a cyclic structure on each end with additional double bonds at the number 5 and 5' carbon atoms of the cyclic structures.

Label: Beta-Carotene

NCI Thesaurus Code: C1016 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0053396  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
.BETA.-CAROTENE
.beta.-Carotene
3,7,12,16-tetramethyl-1,18-bis(2,6,6-trimethyl-1-cyclohexenyl)-octadeca-1,3,5,7,9,11,13,15,17-nonaene
Beta-Carotene
Beta-carotene
beta-Carotene
Beta Carotene
beta carotene
CAROTENE, BETA
Lumitene
Solatene

External Source Codes: 
CAS Registry Number 7235-40-7 (see NLM ChemIDplus info)
FDA UNII Code 01YAE03M7J
ChEBI ID CHEBI:17579 (see ChEBI info)
NSC Code 62794 (see NCI DTP info)
PDQ Closed Trial Search ID 40992
PDQ Open Trial Search ID 40992 (check for NCI PDQ open clinical trial info)
UMLS CUI C0053396

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Dietary supplement; prevention of photosensitivity reactions in patients with erythropoietic protoporphyria; polymorphous light eruption; chemoprevention for cardiovascular disease and cancer
Chemical_Formula C40H56
code C1016
Contributing_Source CRCH
Contributing_Source FDA
INFOODS CARTB
Legacy_Concept_Name Beta_Carotene
Semantic_Type Pharmacologic Substance
Semantic_Type Vitamin
Unit mcg
USDA_ID 321

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1016

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