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Version: 17.06d (Release date: 2017-06-26)
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Folate Binding Protein E39 Peptide Vaccine (Code C101530)

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Terms & Properties

Preferred Name: Folate Binding Protein E39 Peptide Vaccine

Definition: A cancer vaccine comprised of human leukocyte antigen (HLA) A2 restricted folate binding protein (FBP) epitope E39 (amino acids 191 to 199), with potential immunostimulatory and antineoplastic activity. Upon intradermal injection, FBP E39 peptide vaccine may induce a specific cytotoxic T-lymphocyte (CTL) response against FBP-expressing tumor cell types. FBP is a membrane-bound, tumor-associated antigen highly overexpressed in various tumor cell types, such as in breast, ovarian and endometrial cancers; E 39 is a strong immunogenic peptide.

Label: Folate Binding Protein E39 Peptide Vaccine

NCI Thesaurus Code: C101530 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL435783  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
E39 Peptide Vaccine
FBP E39 Peptide Vaccine
Folate Binding Protein E39 Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 732482
PDQ Open Trial Search ID 732482 (check for NCI PDQ open clinical trial info)
NCI META CUI CL435783

Other Properties:
     Name Value (qualifiers indented underneath)
code C101530
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C101530

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