skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Indium In 111 Anti-CD45 Monoclonal Antibody BC8 (Code C101522)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Indium In 111 Anti-CD45 Monoclonal Antibody BC8

Definition: A radioimmunoconjugate containing the murine IgG1 anti-CD45 monoclonal antibody (MoAb) BC8 labeled with the gamma-emitting isotope indium 111 (In 111), with potential radioimaging application. Upon administration, indium In 111 anti-CD45 monoclonal antibody BC8 binds to CD45 antigen, a receptor protein tyrosine phosphatase expressed on the surface of most of the normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, radioactive In 111 allows for the detection of BC8 distribution and tumor localization using gamma scintigraphy.

Display Name: Indium In 111 Anti-CD45 Monoclonal Antibody BC8

Label: Indium In 111 Anti-CD45 Monoclonal Antibody BC8

NCI Thesaurus Code: C101522 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL435779  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Indium In 111 Anti-CD45 Monoclonal Antibody BC8
Indium In 111 Monoclonal Antibody BC8
In 111 MOAB BC8
In 111 Monoclonal Antibody BC8
monoclonal antibody BC8, indium In 111

External Source Codes: 
PDQ Closed Trial Search ID 732229
PDQ Open Trial Search ID 732229 (check for NCI PDQ open clinical trial info)
NCI META CUI CL435779

Other Properties:
     Name Value (qualifiers indented underneath)
code C101522
Contributing_Source CTRP
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C101522

Mainbox Bottom