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Version: 16.11d (Release date: 2016-11-28)
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Gallium Ga 68-Edotreotide (Code C101369)

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Terms & Properties

Preferred Name: Gallium Ga 68-Edotreotide

Definition: A radioconjugate consisting of the octreotide derivative edotreotide labeled with gallium 68 (Ga-68) with potential application in somatostatin receptor (SSTR) imaging in conjunction with positron emission tomography (PET). Similar to octreotide, gallium Ga 68-edotreotide binds to SSTRs, especially type 2 receptors, present on the cell membranes of many types of neuroendocrine tumor cells and their metastases, thereby allowing for imaging of SSTR-expressing cells upon PET. Gallium Ga 68-edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of the somatostatin analogue octreotide (Tyr3-octreotide or TOC) and chelating the substituted octreotide to Ga-68 via the macrocyclic chelating agent dodecanetetraacetic acid (DOTA).

Display Name: Gallium Ga 68-Edotreotide

Label: Gallium Ga 68-Edotreotide

NCI Thesaurus Code: C101369 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL435549  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Ga-68 DOTA0-Tyr3-octreotide
GALLIUM EDOTREOTIDE GA-68
Gallium Ga 68-DOTATOC
Gallium Ga 68-Edotreotide

External Source Codes: 
FDA UNII Code Y68179SY2L
PDQ Closed Trial Search ID 730130
PDQ Open Trial Search ID 730130 (check for NCI PDQ open clinical trial info)
NCI META CUI CL435549

Other Properties:
Name Value (qualifiers indented underneath)
code C101369
Contributing_Source CTRP
Contributing_Source FDA
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C101369

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