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Version: 17.06d (Release date: 2017-06-26)
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Rintatolimod (Code C1001)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Rintatolimod

Definition: A synthetic derivative of inosinic acid with antiretroviral and immunomodulatory properties. Atvogen acts through a number of pathways to stimulate intracellular antiviral activity of the immune system: it stimulates interferon production; activates the oligoadenylate synthase-RNase L pathway; stimulates natural killer cell activity; and acts as a non-mitogenic stimulator of the immune system. This agent also inhibits replication of human immunodeficiency virus (HIV) in vitro. (NCI04)

Display Name: Rintatolimod

Label: Rintatolimod

NCI Thesaurus Code: C1001 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1434913  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Ampligen
Atvogen
Poly(I).Poly(c12,U)
Poly(Inosinic Acid) Poly(Cytidylic(12), Uridylic)Acid
Rintatolimod
RINTATOLIMOD

External Source Codes: 
CAS Registry Number 38640-92-5 (see NLM ChemIDplus info)
FDA UNII Code 94325AJ25N
NSC Code 616524 (see NCI DTP info)
PDQ Closed Trial Search ID 39061
PDQ Open Trial Search ID 39061 (check for NCI PDQ open clinical trial info)
UMLS CUI C1434913

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula ((C9H11N2O8P)n(C9H12N3O7P)n)ran.(C10H11N4O7P)n
code C1001
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Atvogen
Semantic_Type Nucleic Acid, Nucleoside, or Nucleotide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1001

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