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Version: 14.12e (Release date: 2014-12-29-08:00)
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Deoxycytidine Analogue TAS-109 (Code C82697)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Deoxycytidine Analogue TAS-109

Definition: An analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.

Display Name: Deoxycytidine Analogue TAS-109

Label: Deoxycytidine Analogue TAS-109

NCI Thesaurus Code: C82697 (Search for linked caDSR metadata)

NCI Metathesaurus CUI: CL388479  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Deoxycytidine Analogue TAS-109
TAS-109

External Source Codes: 
NCI META CUI CL388479 (see NCI Metathesaurus info)
PDQ Closed Trial Search ID 633936 (check for NCI PDQ closed clinical trial info)
PDQ Open Trial Search ID 633936 (check for NCI PDQ open clinical trial info)

Other Properties:
code C82697
Contributing_Source CTRP
Legacy_Concept_Name Deoxycytidine_Analogue_TAS-109
Semantic_Type Nucleic Acid, Nucleoside, or Nucleotide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C82697&ns=NCI_Thesaurus

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