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Version: 14.12e (Release date: 2014-12-29-08:00)
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GI-4000 Vaccine (Code C61489)

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Terms & Properties

Preferred Name: GI-4000 Vaccine

Definition: A vaccine containing a heat-killed recombinant Saccharomyces cerevisiae yeast transfected with mutated forms of Ras, an oncogene frequently found in solid tumors, with potential immunostimulant and antitumor activity. Upon administration, GI-4000 vaccine elicits an immune response by stimulating a specific cytotoxic T-cell response against the mutated forms of Ras. This may lead to a destruction of cancer cells expressing a Ras mutation.

Display Name: GI-4000 Vaccine

Label: GI-4000 Vaccine

NCI Thesaurus Code: C61489 (Search for linked caDSR metadata)

Synonyms & Abbreviations: (see Synonym Details)
GI-4000 Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 486259 (check for NCI PDQ closed clinical trial info)
PDQ Open Trial Search ID 486259 (check for NCI PDQ open clinical trial info)
UMLS CUI C1831831

Other Properties:
code C61489
Contributing_Source CTRP
Legacy_Concept_Name GI-4000_Vaccine
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61489&ns=NCI_Thesaurus

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