|BIBX 1382 (Code C2539)|
|Terms & Properties|
Preferred Name: BIBX 1382
Definition: A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation.
NCI-GLOSS Definition: A drug that may inhibit tumor cells from multiplying. It is being studied for its ability to treat cancer.
Label: BIBX 1382
NCI Thesaurus Code: C2539 (Search for linked caDSR metadata)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|PDQ Closed Trial Search ID||43568 (check for NCI PDQ closed clinical trial info)|
|PDQ Open Trial Search ID||43568 (check for NCI PDQ open clinical trial info)|
Additional Concept Data:
|Defined Fully by Roles: No|