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Interferon Alfacon-1 (Code C1766)

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Terms & Properties

Preferred Name: Interferon Alfacon-1

Definition: An analogue of consensus interferon which contains an additional methionyl amino acid residue. Consensus interferon (also known as interferon alfacon-1, rCon-IFN, and CIFN) is a genetically engineered synthetic interferon created from the most common amino acid sequences from the naturally occurring alpha interferons. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune-modulating effects.

Label: Interferon Alfacon-1

NCI Thesaurus Code: C1766 (Search for linked caDSR metadata)

Synonyms & Abbreviations: (see Synonym Details)
Advaferon
CIFN
Consensus Interferon
IFN Alfacon-1
Infergen
INTERFERON ALFACON-1
Interferon Alfacon-1
Interferon Consensus, Methionyl
interferon consensus, methionyl
Methionyl-Interferon-Consensus
Methionyl Interferon Consensus
methionyl interferon consensus
r-metHuIFN-Con1
Recombinant Consensus Interferon
Recombinant methionyl human consensus interferon

External Source Codes: 
CAS Registry Number 118390-30-0 (see NLM ChemIDplus info)
FDA UNII Code 56588OP40D
PDQ Closed Trial Search ID 42870 (check for NCI PDQ closed clinical trial info)
PDQ Open Trial Search ID 42870 (check for NCI PDQ open clinical trial info)
UMLS CUI C0164613

Other Properties:
code C1766
Contributing_Source FDA
In_Clinical_Trial_For Metastatic Renal Cell Carcinoma Lacking gp160 Expression.
Legacy_Concept_Name Interferon_Alfacon-1
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1766&ns=NCI_Thesaurus

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