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Version: 14.12e (Release date: 2014-12-29-08:00)
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Recombinant Granulocyte Colony-Stimulating Factor (Code C1287)

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Terms & Properties

Preferred Name: Recombinant Granulocyte Colony-Stimulating Factor

Definition: A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04)

Label: Recombinant Granulocyte Colony-Stimulating Factor

NCI Thesaurus Code: C1287 (Search for linked caDSR metadata)

Synonyms & Abbreviations: (see Synonym Details)
Recombinant Colony-Stimulating Factor 3
Recombinant Granulocyte Colony-Stimulating Factor
rhG-CSF

External Source Codes: 
CAS Registry Number 143011-72-7 (see NLM ChemIDplus info)
NSC Code 614371 (see NCI DTP info)
NSC Code 614629 (see NCI DTP info)
PDQ Closed Trial Search ID 618712 (check for NCI PDQ closed clinical trial info)
PDQ Open Trial Search ID 618712 (check for NCI PDQ open clinical trial info)
UMLS CUI C0376562

Other Properties:
Accepted_Therapeutic_Use_For Neutropenia
code C1287
In_Clinical_Trial_For Chemotherapy-induced neutropenia
Legacy_Concept_Name Recombinant_Granulocyte_Colony_Stimulating_Factor
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: Yes  

URL: http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1287&ns=NCI_Thesaurus

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