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Version: 14.12e (Release date: 2014-12-29-08:00)
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Gabapentin (Code C1108)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Gabapentin

Definition: A synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown, gabapentin appears to inhibit excitatory neuron activity. This agent also exhibits analgesic properties. (NCI04)

NCI-GLOSS Definition: A substance that is being studied as a treatment for relieving hot flashes in women with breast cancer. It belongs to the family of drugs called anticonvulsants.

Display Name: Gabapentin

Label: Gabapentin

NCI Thesaurus Code: C1108 (Search for linked caDSR metadata)

Synonyms & Abbreviations: (see Synonym Details)
1-(aminomethyl)cyclohexaneacetic Acid
Gabapentin
GABAPENTIN
gabapentin
Gralise
Neurontin

External Source Codes: 
CAS Registry Number 60142-96-3 (see NLM ChemIDplus info)
FDA UNII Code 6CW7F3G59X
PDQ Closed Trial Search ID 38402 (check for NCI PDQ closed clinical trial info)
PDQ Open Trial Search ID 38402 (check for NCI PDQ open clinical trial info)
UMLS CUI C0060926

Other Properties:
Accepted_Therapeutic_Use_For Management of Epilepsy; Pain; Mania; Depression and Anxiety Disorders; Postherpetic Neuralgia
Chemical_Formula C9H17NO2
code C1108
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Gabapentin
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1108&ns=NCI_Thesaurus

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